Integrate sequencing data (Variant call format, e.g. VCF or BCF) or meta-analysis results in R. This package can help you (1) read VCF/BCF/BGEN files by chromosomal ranges (e.g. 1:100-200); (2) read RareMETAL summary statistics files; (3) read tables from a tabix-indexed files; (4) annotate VCF/BCF files; (5) create customized workflow based on Makefile.

S4 class object for creating and managing group sequential designs. It calculates the efficacy and futility boundaries at each look. It allows modifying the design and tracking the design update history.

Based on the structure of the SPSS version of the Swiss
    Household Panel (SHP) data, provides a function seqFromWaves()
    that seeks the data of variables specified by the user in each 
    of the wave files and collects them as sequences. The function also 
    matches the sequences with variables from other files such as the 
    master files of persons (MP) and households (MH), and social origins (SO). 
    It can also match with activity calendar data (CA).

Implementation of sequential trial emulation for the analysis of observational databases.
    The 'SEQTaRget' software accommodates time-varying treatments and confounders, as well as binary
    and failure time outcomes. 'SEQTaRget' allows to compare both static and dynamic strategies,
    can be used to estimate observational analogs of intention-to-treat
    and per-protocol effects, and can adjust for potential selection bias
    induced by losses-to-follow-up. (Paper to come).

Sequential triangular test for the arithmetic mean in one- and two-
    samples, proportions in one- and two-samples, and the Pearson's correlation
    coefficient.

A collection of Radix Tree and Trie algorithms for finding similar sequences and calculating sequence distances (Levenshtein and other distance metrics). This work was inspired by a trie implementation in Python: "Fast and Easy Levenshtein distance using a Trie." Hanov (2011) <https://stevehanov.ca/blog/index.php?id=114>.