Allows users to produce estimates and MSE for multivariate variables using Linear Mixed Model. The package follows the approach of Datta, Day and Basawa (1999) <doi:10.1016/S0378-3758(98)00147-5>.

66 data sets that were imported using read.table() where appropriate but more commonly after converting to a csv file for importing via read.csv().

Convert Markdown ('.md') or R Markdown ('.Rmd') texts, R scripts, directory structures, and other hierarchical structured documents into mind map widgets or 'Freemind' codes or 'Mermaid' mind map codes, and vice versa. 'Freemind' mind map ('.mm') files can be opened by or imported to common mind map software such as 'Freemind' (<https://freemind.sourceforge.io/wiki/index.php/Main_Page>). 'Mermaid' mind map codes (<https://mermaid.js.org/>) can be directly embedded in documents.

Citrus is a computational technique developed for the analysis
    of high dimensional cytometry data sets. This package extracts, statistically
    analyzes, and visualizes marker expression from 'citrus' data. This code was used to 
    generate data for Figures 3 and 4 in the forthcoming manuscript: Throm et al. 
    “Identification of Enhanced Interferon-Gamma Signaling in Polyarticular Juvenile 
    Idiopathic Arthritis with Mass Cytometry”, JCI-Insight. For more information on Citrus,
    please see: Bruggner et al. (2014) <doi:10.1073/pnas.1408792111>. To download
    the 'citrus' package, please see <https://github.com/nolanlab/citrus>.

The nonparametric two-stage Bayesian adaptive design is a novel phase II clinical trial design for finding the minimum effective dose (MinED). This design is motivated by the top priority and concern of clinicians when testing a new drug, which is to effectively treat patients and minimize the chance of exposing them to subtherapeutic or overly toxic doses. It is used to design single-agent trials.

Wrapper for 'minepy' implementation of Maximal
        Information-based Nonparametric Exploration statistics (MIC and
        MINE family). Detailed information of the ANSI C implementation of
	'minepy' can be found at <http://minepy.readthedocs.io/en/latest>.