Download files hosted on 'AWS S3' (Amazon Web Services Simple Storage Service; <https://aws.amazon.com/s3/>) to a local directory based on their URI. Avoid downloading files that are already present locally.  Allow for customization of where to store downloaded files.

A S3 resource is provided by Amazon Web Services S3 or a S3-compatible object store (such as Minio). 
    The resource can be a tidy file to be downloaded from the object store, or a data lake (such as Delta Lake) 
    Parquet file to be read by Apache Spark.

Access 'Amazon Web Service Simple Storage Service' ('S3') <https://aws.amazon.com/s3/>
    as if it were a file system. Interface based on the R package 'fs'.

Performs variable selection using the structured screen-and-select (S3VS) framework in linear models, generalized linear models with binary data, and survival models such as the Cox model and accelerated failure time (AFT) model.

Implements a set of distribution modeling methods that are suited to species with small sample sizes (e.g., poorly sampled species or rare species). While these methods can also be used on well-sampled taxa, they are united by the fact that they can be utilized with relatively few data points. More details on the currently implemented methodologies can be found in Drake and Richards (2018) <doi:10.1002/ecs2.2373>, Drake (2015) <doi:10.1098/rsif.2015.0086>, and Drake (2014) <doi:10.1890/ES13-00202.1>.

A new object oriented programming system designed to be a
    successor to S3 and S4. It includes formal class, generic, and method
    specification, and a limited form of multiple dispatch. It has been
    designed and implemented collaboratively by the R Consortium
    Object-Oriented Programming Working Group, which includes
    representatives from R-Core, 'Bioconductor', 'Posit'/'tidyverse', and
    the wider R community.

Perform joint segmentation on two signal dimensions derived from 
    total read depth (intensity) and allele specific read depth (intensity) for 
    whole genome sequencing (WGS), whole exome sequencing (WES) and SNP array data.