Functions for cost-sensitive multi-criteria ensemble selection (CSMES) (as described in De bock et al. (2020) <doi:10.1016/j.ejor.2020.01.052>) for cost-sensitive learning under unknown cost conditions.

Implements the conditionally symmetric multidimensional Gaussian mixture model (csmGmm) for large-scale testing of composite null hypotheses in genetic association applications such as mediation analysis, pleiotropy analysis, and replication analysis. In such analyses, we typically have J sets of K test statistics where K is a small number (e.g. 2 or 3) and J is large (e.g. 1 million). For each one of the J sets, we want to know if we can reject all K individual nulls. Please see the vignette for a quickstart guide. The paper describing these methods is "Testing a Large Number of Composite Null Hypotheses Using Conditionally Symmetric Multidimensional Gaussian Mixtures in Genome-Wide Studies" by Sun R, McCaw Z, & Lin X (Journal of the American Statistical Association 2025, <doi:10.1080/01621459.2024.2422124>).

Provides functions for computing the density
    and the log-likelihood function of closed-skew normal variates,
    and for generating random vectors sampled from this distribution.
    See Gonzalez-Farias, G., Dominguez-Molina, J., and Gupta, A. (2004).
    The closed skew normal distribution, 
    Skew-elliptical distributions and their applications: a journey beyond normality,
    Chapman and Hall/CRC, Boca Raton, FL, pp. 25-42.

Imports 'PxStat' data in JSON-stat format and (optionally) reshapes it into wide
	format. The Central Statistics Office (CSO) is the national statistical institute of Ireland
	and 'PxStat' is the CSOs online database of Official Statistics. This database contains current
	and historical data series compiled from CSO statistical releases and is accessed at
	<https://data.cso.ie>.
	The CSO 'PxStat' Application Programming Interface (API), which is accessed in this package, provides
	access to 'PxStat' data in JSON-stat format at <https://data.cso.ie>.
	This dissemination tool allows developers machine to machine access to CSO 'PxStat' data.