Obtaining relevant set of trait specific genes from gene expression data is important for clinical diagnosis of disease and discovery of disease mechanisms in plants and animals. This process involves identification of relevant genes and removal of redundant genes as much as possible from a whole gene set. This package returns the trait specific gene set from the high dimensional RNA-seq count data by applying combination of two conventional machine learning algorithms, support vector machine (SVM) and genetic algorithm (GA). GA is used to control and optimize the subset of genes sent to the SVM for classification and evaluation. Genetic algorithm uses repeated learning steps and cross validation over number of possible solution and selects the best. The algorithm selects the set of genes based on a fitness function that is obtained via support vector machines. Using SVM as the classifier performance and the genetic algorithm for feature selection, a set of trait specific gene set is obtained.

To provide a high dimensional grouped variable selection approach for detection of whole-genome SNP effects and SNP-SNP interactions, as described in Fang et al. (2017, under review).

Two-stage procedure compares hazard rate functions,
    which may or may not cross each other.

Provides a 'tbl_ts' class (the 'tsibble') for
    temporal data in an data- and model-oriented format. The 'tsibble'
    provides tools to easily manipulate and analyse temporal data, such as
    filling in time gaps and aggregating over calendar periods.

Provides diverse datasets in the 'tsibble' data structure. These datasets are useful for learning and demonstrating how tidy temporal data can tidied, visualised, and forecasted.

A shared tsibble data easily communicates between
    htmlwidgets on both client and server sides, powered by 'crosstalk'. A
    shiny module is provided to visually explore periodic/aperiodic
    temporal patterns.

Time series methods for intermittent demand forecasting. Includes Croston's method and its variants (Moving Average, SBA), and the TSB method. Users can obtain optimal parameters on a variety of loss functions, or use fixed ones (Kourenztes (2014) <doi:10.1016/j.ijpe.2014.06.007>). Intermittent time series classification methods and iMAPA that uses multiple temporal aggregation levels are also provided (Petropoulos & Kourenztes (2015) <doi:10.1057/jors.2014.62>).