Performs receptor abundance estimation for single cell RNA-sequencing data using a supervised feature selection mechanism and a thresholded gene set scoring procedure. Seurat's normalization method is described in: Hao et al., (2021) <doi:10.1016/j.cell.2021.04.048>, Stuart et al., (2019) <doi:10.1016/j.cell.2019.05.031>, Butler et al., (2018) <doi:10.1038/nbt.4096> and Satija et al., (2015) <doi:10.1038/nbt.3192>. Method for reduced rank reconstruction and rank-k selection is detailed in: Javaid et al., (2022) <doi:10.1101/2022.10.08.511197>. Gene set scoring procedure is described in: Frost et al., (2020) <doi:10.1093/nar/gkaa582>. Clustering method is outlined in: Song et al., (2020) <doi:10.1093/bioinformatics/btaa613> and Wang et al., (2011) <doi:10.32614/RJ-2011-015>.

A framework for data stream modeling and associated data
    mining tasks such as clustering and classification. The development of
    this package was supported in part by NSF IIS-0948893, NSF CMMI
    1728612, and NIH R21HG005912. Hahsler et al (2017)
    <doi:10.18637/jss.v076.i14>.

Numerically solve and plot solutions of a parametric ordinary
        differential equations model of growth, death, and respiration of
        macroinvertebrate and algae taxa dependent on pre-defined environmental
        factors. The model (version 1.0) is introduced in Schuwirth, N. and
        Reichert, P., (2013) <DOI:10.1890/12-0591.1>. This package includes
        model extensions and the core functions introduced and used in
        Schuwirth, N. et al. (2016) <DOI:10.1111/1365-2435.12605>,
        Kattwinkel, M. et al. (2016) <DOI:10.1021/acs.est.5b04068>,
        Mondy, C. P., and Schuwirth, N. (2017) <DOI:10.1002/eap.1530>,
        and Paillex, A. et al. (2017) <DOI:10.1111/fwb.12927>.

Tools for using the 'StreamCat' and 'LakeCat' API and 
             interacting with the 'StreamCat' and 'LakeCat' database. 
             Convenience functions in the package wrap the API for 'StreamCat' 
             on <https://api.epa.gov/StreamCat/streams/metrics>.